Chromogranin a and ppi
WebApr 12, 2002 · Chromogranin A (CgA) is a general marker associated with all carcinoid tumors. It is a protein produced by tumor cells and released. Chromogranin A is associated with other hormones and may be involved in their regulation. It may also be associated with cell adhesion in metastatic disease. Webthe most common culprit is the use of PPIs [ 3,5]. Hyperchromograninemia resulting from PPI use is typi-cally moderate with no associated symptoms reported, and with …
Chromogranin a and ppi
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WebA critical requirement in neuroendocrine tumor (NET) management is a blood biomarker test that is sensitive, specific and reproducible. We evaluated a PCR-based 51-transcript signature to detect tumors, compared it with chromogranin A (CgA) and examined the confounding effect of proton pump inhibitors (PPIs), which cause falsely elevated CgA … WebDec 20, 2024 · Numerous immunoassays have been developed to measure the levels of chromogranin A (CgA), a useful biomarker for diagnosing and monitoring generally heterogeneous neuroendocrine tumors (NETs). Here, we evaluated the imprecision and linearity of three such assays: KRYPTOR (ThermoFisher Scientific), NEOLISA …
WebMar 9, 2024 · The Pearson correlation test revealed a positive and significant linear correlation between the Ki-67 index and chromogranin A level, r = 0.626, p < 0.001. No significant (p = 0.49) correlation was found between the level of gastrin and the level of chromogranin A. The anti-parietal cell antibody was positive in 12/12 patients tested. WebSome PPI users develop fundic gland polyps. The purpose of this study was to determine whether patients developing fundic gland polyps have a more pronounced gastric hypoacidity, hypergastrinemia or increased serum chromogranin A (CgA), which is an enterochromaffin-like (ECL) cell marker.
WebContext: Chromogranin A (CgA) is used as a generic tumor marker for neuroendocrine tumors. Proton pump inhibitors (PPI) are known to increase CgA, but it is not clear to … WebChromogranin A is a protein stored and released with peptides and amines in a variety of neuroendocrine tissues. The plasma level of chromogranin A in patients with neuroendocrine tumors has a sensitivity and specificity of 75% and 84%, respectively. Chromogranin A levels increase with tumor burden.
WebOct 11, 2011 · Chromogranin A is localised in the secretory granules of the neuroendocrine cells. Chromogranin A levels may also be elevated in other disease processes, such as …
WebApr 24, 2024 · It would be a good idea to inquire if your doctor would do these lab tests as well. From what my GI doctor has told me that the Chromogranin A Level can be high if … the original sonic the hedgehog movieWebA well-known side effect of PPI therapy that may cause serious differential diagnostic problems is the elevation of serum chromogranin A (CgA). Objective: We report a case with highly elevated serum CgA in a patient with bilateral adrenal adenomas that was clearly associated with PPI therapy. the originals online español latinoWebProton pump inhibitors (PPIs), including esomeprazole, are contraindicated in patients receiving rilpivirine containing products [see Drug Interactions ] ... Serum chromogranin A (CgA) levels increase secondary to drug-induced decreases in gastric acidity. The increased CgA level may cause false positive results in diagnostic investigations for ... the originals online free watchWebSep 30, 2024 · Studies have shown a fairly strong statistical correlation between PPI use and C. difficile infection, although it's still just a correlation and not proof of direct cause and effect. Some experimental evidence suggests that PPIs may change conditions in the gut to be more favorable to C. difficile bacteria. Iron and B12 deficiency. the originals on legaciesWebChromogranin A (CgA) is regarded as a major, nonspecific neuroendocrine tumour (NET) marker. The results of CgA blood concentration, however, may actually be influenced by … the originals online hdWebNontumor-related elevations of Chromogranin A can be observed in gastrointestinal, cardiovascular, and renal disorders, as well as with proton pump inhibitor (PPI) therapy. … the originals online sa prevodom filmoviplexWebChromogranin A (CgA) is regarded as a major, nonspecific neuroendocrine tumour (NET) marker. The results of CgA blood concentration, however, may actually be influenced by various factors or coexisting pathological conditions. Among the factors causing a substantial increase of the blood CgA concent … the originals online pl